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Important Safety Information
What is UPNEEQ?

UPNEEQ™ is a prescription eyedrops used to treat low eyelid height (acquired blepharoptosis) in adults.

What warnings and precautions are associated with UPNEEQ?
  • UPNEEQ is a type of medication than may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
  • Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjogren’s syndrome) should use care when taking UPNEEQ. Call your doctor immediately if you feel your symptoms may be getting worse.
  • UPNEEQ may increase the risk fo blocked vision (angle closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor if your vision gets worse after using UPNEEQ.
  • Do not let the tip fo the UPNEEQ vial touch your eye or any other surface. This can help prevent injury or contamination.
What are the possible side effects of UPNEEQ?

The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, installation site pain, eye irritation, and headache.

What medications should my healthcare provider know I’m using before I use UPNEEQ?
  • UPNEEQ belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use UPNEEQ carefully if you currently take an alpha-adrenergic agonist medication to treat heart disease or an enlarged prostate. Patient taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat should also be careful when using UPNEEQ.
  • Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using UPNEEQ, as it may affect the way your body absolves the medication.
Please click here for full Prescribing Information.